Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 15/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439798 | 0.85 | BDKRB1 (0.62) | BDKRB1 | |
| SCHEMBL12012120 | 0.80 | BDKRB1 (0.39) | BDKRB1 | |
| SCHEMBL12010197 | 0.80 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL12010173 | 0.80 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL12047260 | 0.80 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL10118698 | 0.79 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL12047239 | 0.77 | BDKRB1 (0.38) | BDKRB1 | |
| SCHEMBL12012116 | 0.77 | BDKRB1 (0.44) | BDKRB1 | |
| SCHEMBL13063102 | 0.77 | BDKRB1 (0.38) | BDKRB1 | |
| SCHEMBL13063417 | 0.77 | MCHR1 (0.34) | BDKRB1MCHR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858618-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20090137545-A1 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137545-A1 | Compounds | ADORA2B, ABCB11, CYP11B1 | BDKRB1 6/4885MCHR1 587/4885HTR2A 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.