Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784521 | 0.92 | CCR2 (0.38) | SMN1; SMN2MEN1KMT2AKCNH2CHRM4 | |
| Hydrochloric Acid SCHEMBL3782275 | 0.91 | CCR2 (0.38) | SMN1; SMN2MEN1KMT2AKCNH2CHRM4 | |
| SCHEMBL13806694 | 0.85 | TACR1 (0.37) | SMN1; SMN2MEN1KMT2AKCNH2CHRM4 | |
| SCHEMBL3790440 | 0.84 | CCR2 (0.43) | GAASMN1; SMN2KCNH2CYP3A4CYP2D6 | |
| SCHEMBL3784130 | 0.80 | CCR2 (0.43) | GAASMN1; SMN2KCNH2CYP2D6 | |
| SCHEMBL3787224 | 0.79 | CCR2 (0.39) | SMN1; SMN2MEN1KMT2AMCHR1KCNH2 | |
| SCHEMBL13063405 | 0.73 | PARP1 (0.47) | KMT2AMCHR1KCNH2MCHR2 | |
| SCHEMBL13063421 | 0.71 | CCR2 (0.43) | GAASMN1; SMN2MCHR1KCNH2CYP3A4 | |
| SCHEMBL3788883 | 0.71 | CCR2 (0.43) | GAASMN1; SMN2MCHR1KCNH2CYP3A4 | |
| SCHEMBL3791324 | 0.70 | CCR2 (0.45) | KCNH2CYP3A4CYP2D6MCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CYTOPATHFINDER, INC. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CCR2, CCR1, CCR5 | CTSC 430/4885GAA 3620/4885SMN1; SMN2 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.