Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 7/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904371 | 1.00 | NFKB1 (0.59) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL14923296 | 0.98 | NFKB1 (0.57) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL23522374 | 0.94 | NFKB1 (0.59) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL29362349 | 0.94 | NFKB1 (0.59) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL8734157 | 0.92 | NFKB1 (0.49) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL29359665 | 0.90 | NFKB1 (0.55) | NFKB1NFKB2RELAEPHX2PARP1 | |
| Alterporriol A/B SCHEMBL30948399 | 0.89 | NFKB1 (0.59) | NFKB1NFKB2RELAEPHX2PARP1 | |
| Alterporriol G/H SCHEMBL15338594 | 0.88 | NFKB1 (0.55) | NFKB1NFKB2RELAEPHX2PARP1 | |
| Alterporriol G/H SCHEMBL904379 | 0.88 | NFKB1 (0.55) | NFKB1NFKB2RELAEPHX2PARP1 | |
| SCHEMBL23522462 | 0.87 | NFKB1 (0.67) | NFKB1NFKB2RELAPARP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135759-A1 | NOVEL ANTHRAQUINONE DERIVATIVES | SEALIFE PHARMA GMBH (AT) | 2010-12-02 | — | — | WO | disclosed |