Alterporriol A/B

SCHEMBL30948399

COc1cc(O)c2c(c1-c1c(OC)cc(O)c3c1C(=O)c1cc(C)c(O)cc1C3=O)C(=O)C1=C(C2=O)[C@H](O)[C@@H](O)[C@](C)(O)[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NFKB1	P19838	1/20	0.59

▸	NFKB2	Q00653	1/20	0.59

▸	RELA	Q04206	1/20	0.59

▸	PARP1	P09874	9/20	0.36

▸	PTPN1	P18031	9/20	0.36

▸	TERT	O14746	2/20	0.34

▸	EGFR	P00533	2/20	0.33

▸	IDO1	P14902	2/20	0.33

▸	EPHX2	P34913	2/20	0.32

▸	PIM1	P11309	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Alterporriol G/H SCHEMBL904379	0.93	NFKB1 (0.55)	NFKB1NFKB2RELAPARP1PTPN1
Alterporriol G/H SCHEMBL15338594	0.93	NFKB1 (0.55)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL23522462	0.90	NFKB1 (0.67)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL29360017	0.90	NFKB1 (0.67)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL13063713	0.89	NFKB1 (0.59)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL904371	0.89	NFKB1 (0.59)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL29362349	0.89	NFKB1 (0.59)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL23522374	0.89	NFKB1 (0.59)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL14923296	0.87	NFKB1 (0.57)	NFKB1NFKB2RELAPARP1PTPN1
SCHEMBL29359665	0.83	NFKB1 (0.55)	NFKB1NFKB2RELAPARP1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111967139-B	Ceramic-based fiber bundle composite material elastic modulus calculation method considering defect influence	南京航空航天大学	2024-06-11	—	—	CN	disclosed