Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14160604 | 0.79 | ADRB2 (0.35) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL25919320 | 0.76 | ADRB2 (0.42) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL3290589 | 0.75 | TSHR (0.41) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL8987497 | 0.75 | ADRB2 (0.39) | ADRB2ADRB1ADRB3CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL27502470 | 0.74 | ADRB2 (0.40) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL30940577 | 0.73 | ADRB2 (0.38) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL4921403 | 0.73 | ADRB2 (0.39) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL7447362 | 0.71 | CYP3A4 (0.37) | ADRB2ADRB1ADRB3CA1CA2 | |
| SCHEMBL13825811 | 0.71 | ADRB2 (0.36) | ADRB2ADRB1ADRB3CYP3A4TSHR | |
| SCHEMBL11003484 | 0.71 | TSHR (0.42) | ADRB2ADRB1ADRB3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127159-A2 | POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127154-A1 | POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | WO | disclosed |