Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.36 |
| ▸ | LPL | P06858 | 5/20 | 0.36 |
| ▸ | F11 | P03951 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021403 | 0.85 | LIPG (0.43) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL29377126 | 0.81 | ERN1 (0.49) | ROCK1LIPGLPL | |
| SCHEMBL22465928 | 0.81 | ERN1 (0.49) | ROCK1LIPGLPL | |
| SCHEMBL16011263 | 0.80 | ROCK1 (0.44) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL16021406 | 0.80 | ROCK1 (0.40) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL14488668 | 0.78 | ROCK1 (0.39) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL780202 | 0.77 | ROCK1 (0.39) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL14488072 | 0.76 | ROCK1 (0.38) | ROCK1LIPGLPLF11F2 | |
| SCHEMBL23124209 | 0.76 | LPL (0.43) | ROCK1LIPGLPLF11CA1 | |
| SCHEMBL19647680 | 0.75 | ROCK1 (0.40) | ROCK1LIPGLPLF11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138598-A2 | LXR MODULATORS | EXELIXIS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |