Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242802 | 0.72 | MEN1 (0.50) | KDM4EGAAL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL13064325 | 0.72 | KDM4E (0.49) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL25028183 | 0.70 | DPP4 (0.49) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL10301435 | 0.70 | DPP4 (0.49) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL290464 | 0.69 | KDM4E (0.46) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL289837 | 0.69 | DPP4 (0.53) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL288846 | 0.68 | KDM4E (0.84) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL298591 | 0.68 | KDM4E (0.64) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL290222 | 0.67 | KDM4E (0.64) | KDM4EGAAL3MBTL1GLARAB9A | |
| SCHEMBL298601 | 0.67 | KDM4E (0.50) | KDM4EGAAL3MBTL1GLARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |