Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418775 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL290222 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289699 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289704 | 0.83 | KDM4E (0.79) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL288534 | 0.83 | KDM4E (0.86) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289139 | 0.83 | KDM4E (0.86) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289408 | 0.83 | SMN1; SMN2 (0.72) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289248 | 0.82 | KDM4E (0.77) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL289908 | 0.82 | KDM4E (0.76) | KDM4EALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL288501 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1GAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |