Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.66 |
| ▸ | CA1 | P00915 | 11/20 | 0.66 |
| ▸ | CA9 | Q16790 | 7/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064158 | 0.83 | CA2 (0.64) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL10445738 | 0.78 | CA2 (0.56) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL9403476 | 0.78 | CA2 (0.56) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL19383055 | 0.77 | CA2 (0.69) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL9403489 | 0.76 | CA2 (0.66) | CA2CA1CA9CA5ACA7 | |
| Bromide SCHEMBL9403443 | 0.75 | CA2 (0.65) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL13064363 | 0.74 | SMN1; SMN2 (0.60) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL24599301 | 0.71 | CA2 (0.79) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL13764562 | 0.71 | CA2 (1.00) | CA2CA1CA9CA5ACA7 | |
| SCHEMBL24599407 | 0.70 | CA1 (1.00) | CA2CA1CA9CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147666-A1 | COMPOUNDS USEFUL AS CARBONIC ANHYDRASE MODULATORS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2010-12-23 | — | — | WO | disclosed |