Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.64 |
| ▸ | CA1 | P00915 | 14/20 | 0.64 |
| ▸ | CA5A | P35218 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 7/20 | 0.48 |
| ▸ | CA3 | P07451 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064370 | 0.83 | CA2 (0.66) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL10445738 | 0.80 | CA2 (0.56) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL9403476 | 0.80 | CA2 (0.56) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL19383055 | 0.78 | CA2 (0.69) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL9403489 | 0.77 | CA2 (0.66) | CA2CA1CA5ACA7CA5B | |
| Bromide SCHEMBL9403443 | 0.76 | CA2 (0.65) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL13764562 | 0.72 | CA2 (1.00) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL24599307 | 0.70 | CA2 (1.00) | CA2CA1CA5ACA7CA5B | |
| SCHEMBL31653957 | 0.69 | CHRNB2 (0.54) | — | |
| SCHEMBL9403531 | 0.69 | CA2 (0.56) | CA2CA1CA5ACA7CA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147666-A1 | COMPOUNDS USEFUL AS CARBONIC ANHYDRASE MODULATORS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2010-12-23 | — | — | WO | disclosed |