Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | CNR2 | P34972 | 3/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456953 | 0.92 | LMNA (0.79) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL303420 | 0.92 | LMNA (0.72) | LMNAKMT2AHPGDCNR2HTT | |
| SCHEMBL13064393 | 0.91 | LMNA (0.60) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065007 | 0.90 | LMNA (0.86) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065194 | 0.89 | HPGD (0.73) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL302271 | 0.89 | LMNA (0.68) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065202 | 0.89 | CNR2 (0.60) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL1723232 | 0.88 | LMNA (0.54) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13064516 | 0.88 | LMNA (0.60) | LMNAKMT2AHPGDCNR2CNR1 | |
| SCHEMBL13065216 | 0.85 | LMNA (0.63) | LMNAKMT2AHPGDCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |