Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13551889 | 1.00 | PKM (0.41) | PKMGAAABCB1ARSMN1; SMN2 | |
| SCHEMBL16358081 | 0.83 | GAA (0.36) | GAAABCB1AR | |
| SCHEMBL13551888 | 0.83 | AR (0.33) | GAAABCB1ARMMP2MMP9 | |
| SCHEMBL13064590 | 0.83 | AR (0.33) | GAAABCB1ARMMP2MMP9 | |
| SCHEMBL13551890 | 0.82 | GAA (0.33) | GAAABCB1AR | |
| SCHEMBL847973 | 0.79 | AR (0.32) | GAAAR | |
| SCHEMBL17445285 | 0.79 | AR (0.32) | GAAAR | |
| SCHEMBL849049 | 0.77 | PKM (0.46) | PKMSMN1; SMN2TDP1POLBALDH1A1 | |
| SCHEMBL13551887 | 0.76 | THRB (0.32) | GAA | |
| SCHEMBL879935 | 0.73 | PKM (0.42) | PKMSMN1; SMN2TDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |