Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | IGLV6-57 | P01721 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL27925750 | 0.90 | MAOA (0.68) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29474940 | 0.88 | MAOA (0.74) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL66891 | 0.88 | MAOA (0.74) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Ethylamine SCHEMBL8340171 | 0.87 | MAOA (0.64) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Alcohol SCHEMBL11228664 | 0.87 | MAOA (0.64) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Dimethylamine SCHEMBL15397889 | 0.86 | MAOA (0.68) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27839067 | 0.86 | MAOA (0.72) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Water SCHEMBL28315263 | 0.86 | MAOA (0.72) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27924128 | 0.86 | MAOA (0.72) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL28811744 | 0.83 | MAOA (0.68) | MAOAALDH1A1LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437048-B | Detection Ag + Coumarin fluorescent probe, preparation method and application thereof | 宁夏师范学院 | 2024-01-09 | — | — | CN | claimed |
| CN-114437048-A | Detect Ag+Coumarin fluorescent probe, preparation method and application thereof | 宁夏师范学院 | 2022-05-06 | — | — | CN | claimed |
| US-6126924-A | Light responsive self-tanning products and methods for use | SCALES-MEDEIROS VIRGINIA A (US) | 2000-10-03 | — | — | US | claimed |
| CN-114437048-B | Detection Ag + Coumarin fluorescent probe, preparation method and application thereof | 宁夏师范学院 | 2024-01-09 | — | — | CN | disclosed |
| CN-114437048-A | Detect Ag+Coumarin fluorescent probe, preparation method and application thereof | 宁夏师范学院 | 2022-05-06 | — | — | CN | disclosed |
| CN-112011055-B | Functional organic silicon resin for adsorbing and light-operated desorption of protein and preparation method thereof | 山东大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-112011055-A | Functional organic silicon resin for adsorbing and light-operated desorption of protein and preparation method thereof | 山东大学 | 2020-12-01 | — | — | CN | disclosed |
| CN-110540549-B | Coumarin group bridged silane and preparation method thereof | 山东大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-110540549-B | Coumarin group bridged silane and preparation method thereof | 山东大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-110540549-A | Coumarin group bridged silane and preparation method thereof | UNIV SHANDONG | 2019-12-06 | — | — | CN | disclosed |
| CN-110540549-A | Coumarin group bridged silane and preparation method thereof | UNIV SHANDONG | 2019-12-06 | — | — | CN | disclosed |
| US-8053585-B2 | Protecting group for carboxylic acids that can be photolyzed by visible light | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2008-08-14 | — | — | US | disclosed |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-6126924-A | Light responsive self-tanning products and methods for use | SCALES-MEDEIROS VIRGINIA A (US) | 2000-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194522-A1 | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) | MAOA, MAOB, COMT | MAOA 1/4885ALDH1A1 181/4885LMNA 1952/4885 |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CYBA, ALDH3A1, HCCS | MAOA 77/4885ALDH1A1 37/4885LMNA 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.