Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558665 | 0.85 | CYP17A1 (0.58) | CYP17A1CYP19A1SMN1; SMN2TBXAS1ALDH1A1 | |
| SCHEMBL18513757 | 0.81 | CYP17A1 (0.48) | CYP17A1CYP19A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL28440300 | 0.80 | CYP19A1 (0.42) | CYP17A1CYP19A1F7F3SARM1 | |
| SCHEMBL28299971 | 0.80 | CYP17A1 (0.53) | CYP17A1CYP19A1SMN1; SMN2TBXAS1ALDH1A1 | |
| SCHEMBL4791510 | 0.79 | LMNA (0.37) | CYP17A1CYP19A1LMNA | |
| SCHEMBL19514656 | 0.79 | CYP19A1 (0.53) | CYP17A1CYP19A1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27687109 | 0.79 | SMN1; SMN2 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL9652762 | 0.78 | CYP17A1 (0.52) | CYP17A1CYP19A1SMN1; SMN2TBXAS1ALDH1A1 | |
| SCHEMBL29290709 | 0.78 | CYP17A1 (0.52) | CYP17A1CYP19A1SMN1; SMN2TBXAS1ALDH1A1 | |
| SCHEMBL264866 | 0.78 | HCAR2 (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298270-A1 | Novel Compounds and Methods of Using Them | SYNDAX PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298270-A1 | Novel Compounds and Methods of Using Them | HDAC1, HDAC3, HDAC6 | CYP17A1 674/4885CYP19A1 761/4885F7 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.