Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652762 | 1.00 | CYP17A1 (0.52) | CYP17A1CYP19A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28483924 | 0.84 | TBXAS1 (0.44) | CYP17A1CYP19A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7748909 | 0.83 | LMNA (0.43) | L3MBTL1SMN1; SMN2LMNAKCNA5TBXAS1 | |
| SCHEMBL9652095 | 0.81 | CYP19A1 (0.48) | CYP17A1CYP19A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6242067 | 0.81 | HCAR2 (0.51) | L3MBTL1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5693685 | 0.81 | HCAR2 (0.51) | L3MBTL1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL585143 | 0.81 | HCAR2 (0.51) | L3MBTL1MAPTKDM4EALDH1A1HSD17B10 | |
| Methane SCHEMBL28580094 | 0.80 | HCAR2 (0.50) | L3MBTL1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27558665 | 0.80 | CYP17A1 (0.58) | CYP17A1CYP19A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13065872 | 0.78 | CYP17A1 (0.57) | CYP17A1CYP19A1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641874-A | C for target protein degradation3The glutarimide degron body of carbon connection | C4医药公司 | 2019-04-16 | — | — | CN | disclosed |