Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306594 | 1.00 | CNR2 (0.41) | CNR2KDM4EHPGDALDH1A1CNR1 | |
| SCHEMBL1306595 | 0.93 | CNR2 (0.41) | CNR2KDM4EHPGDALDH1A1CNR1 | |
| SCHEMBL1306593 | 0.93 | CNR2 (0.41) | CNR2KDM4EHPGDALDH1A1CNR1 | |
| SCHEMBL1306109 | 0.92 | HPGD (0.48) | CNR2HPGDALDH1A1CNR1PLAAT3 | |
| SCHEMBL1306108 | 0.92 | HPGD (0.48) | CNR2HPGDALDH1A1CNR1PLAAT3 | |
| SCHEMBL1307532 | 0.91 | ALDH1A1 (0.46) | CNR2KDM4EHPGDALDH1A1TDP1 | |
| SCHEMBL1307535 | 0.91 | ALDH1A1 (0.46) | CNR2KDM4EHPGDALDH1A1TDP1 | |
| SCHEMBL1306924 | 0.90 | HDAC6 (0.42) | KDM4EHPGDALDH1A1TDP1PLAAT3 | |
| SCHEMBL29488475 | 0.90 | HDAC6 (0.42) | KDM4EHPGDALDH1A1TDP1PLAAT3 | |
| SCHEMBL1306921 | 0.90 | HDAC6 (0.42) | KDM4EHPGDALDH1A1TDP1PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |