Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306108 | 1.00 | HPGD (0.48) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1307037 | 0.93 | PTPN1 (0.48) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1307035 | 0.93 | PTPN1 (0.48) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1306595 | 0.92 | CNR2 (0.41) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1306591 | 0.92 | CNR2 (0.41) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1306594 | 0.92 | CNR2 (0.41) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1306593 | 0.92 | CNR2 (0.41) | HPGDMCL1PTPN1PLAAT3PLAAT5 | |
| SCHEMBL1307180 | 0.92 | ALDH1A1 (0.45) | HPGDMCL1PTPN1ALDH1A1LMNA | |
| SCHEMBL1307179 | 0.92 | ALDH1A1 (0.45) | HPGDMCL1PTPN1ALDH1A1LMNA | |
| SCHEMBL1306689 | 0.92 | PTPN1 (0.48) | HPGDMCL1PTPN1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |