Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969558 | 0.80 | CES2 (0.38) | ALDH1A1FFAR3 | |
| SCHEMBL14616970 | 0.77 | — | — | |
| SCHEMBL18867193 | 0.77 | CES1 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL2123312 | 0.76 | ALDH1A1 (0.44) | TDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL18867192 | 0.73 | — | — | |
| SCHEMBL7614203 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SOAT1 | |
| SCHEMBL13433279 | 0.73 | — | — | |
| SCHEMBL16885822 | 0.71 | ALDH1A1 (0.39) | TDP1ALDH1A1FFAR3SOAT1 | |
| SCHEMBL7591611 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL24167939 | 0.70 | HCAR2 (0.35) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002176-A1 | ERK INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002176-A1 | ERK INHIBITORS AND USES THEREOF | MAPK1, MAPK3, MAP4K2 | TDP1 2480/4885ALDH1A1 2289/4885FFAR3 4325/4885 |
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, ZDHHC7 | TDP1 3126/4885ALDH1A1 324/4885FFAR3 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.