Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13066090 | 0.95 | CYP17A1 (0.50) | PTPN11KAT6AMEN1KMT2ANAMPT | |
| SCHEMBL13023726 | 0.89 | L3MBTL1 (0.46) | KAT6AMEN1KMT2ANAMPTRAB9A | |
| SCHEMBL13065996 | 0.87 | HDAC3 (0.49) | KAT6AMEN1KMT2ANAMPTRAB9A | |
| SCHEMBL13023613 | 0.86 | LMNA (0.46) | KAT6AMEN1KMT2ANAMPTRXFP1 | |
| SCHEMBL13023542 | 0.85 | HDAC3 (0.49) | KAT6AMEN1KMT2ANAMPTRAB9A | |
| SCHEMBL13300058 | 0.83 | RXFP1 (0.45) | KAT6AMEN1KMT2ANAMPTRXFP1 | |
| SCHEMBL31396764 | 0.82 | KMT2A (0.59) | KAT6AMEN1KMT2ANAMPTRAB9A | |
| SCHEMBL13350005 | 0.82 | NAMPT (0.56) | PTPN11KAT6AMEN1KMT2ANAMPT | |
| SCHEMBL22669530 | 0.80 | HDAC3 (0.46) | PTPN11KAT6ANAMPTRXFP1HDAC3 | |
| SCHEMBL29467525 | 0.80 | HDAC3 (0.46) | PTPN11KAT6ANAMPTRXFP1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | PTPN11 4656/4885KAT6A 164/4885MEN1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.