Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859396 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL844664 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL859247 | 0.82 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL16998699 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL17689167 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL16998617 | 0.72 | KDM4E (0.47) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL861950 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL859368 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| SCHEMBL859302 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1HPGDRCE1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL859600 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1HPGDRCE1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132999-A1 | METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | CHLORION PHARMA, INC. (CA) | 2010-11-25 | — | — | WO | disclosed |