Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17689167 | 0.79 | KDM4E (0.42) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL858535 | 0.76 | LMNA (0.38) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL845268 | 0.76 | L3MBTL1 (0.40) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL844664 | 0.76 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL844618 | 0.75 | L3MBTL1 (0.39) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL859247 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL861950 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL859368 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL13066697 | 0.74 | KDM4E (0.38) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL859396 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4EHPGDL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITé LAVAL (CA) | 2015-08-13 | — | — | US | disclosed |
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITé LAVAL (CA) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225423-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | ALDH1A1 577/4885KDM4E 3841/4885HPGD 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.