Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12809947 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4ECYP1A2HPGDHSD17B10 | |
| SCHEMBL12647199 | 0.71 | CYP1A2 (0.38) | ALDH1A1KDM4EGAACYP1A2CYP2A6 | |
| SCHEMBL11030483 | 0.69 | TYMP (0.40) | ALDH1A1KDM4EGAACYP1A2CYP2A6 | |
| SCHEMBL24774791 | 0.68 | KDM4E (0.44) | ALDH1A1KDM4EPDK2CYP1A2HPGD | |
| SCHEMBL12647692 | 0.66 | PGR (0.41) | ALDH1A1KDM4ECYP1A2CYP2A6HPGD | |
| SCHEMBL1889878 | 0.66 | PARP1 (0.55) | ALDH1A1KDM4EGAACYP1A2CYP2A6 | |
| SCHEMBL12647196 | 0.64 | PGR (0.43) | ALDH1A1KDM4EGAACYP1A2CYP2A6 | |
| SCHEMBL599191 | 0.62 | CYP1A2 (0.62) | ALDH1A1KDM4EGAACYP1A2CYP2A6 | |
| SCHEMBL8556238 | 0.61 | PDK2 (0.34) | ALDH1A1KDM4EPDK2HPGDPDK4 | |
| SCHEMBL9765525 | 0.61 | AKR1B1 (0.49) | ALDH1A1KDM4EGAACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833756-B2 | Methods of labelling polynucleotides with dibenzorhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-16 | — | — | US | disclosed |