Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 11/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.50 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868337 | 0.93 | SMN1; SMN2 (0.60) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1734880 | 0.85 | NPC1 (0.69) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL28698089 | 0.84 | GPR119 (0.49) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL25875857 | 0.83 | NPC1 (0.49) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL27049175 | 0.83 | SMN1; SMN2 (0.62) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL13067483 | 0.83 | NPC1 (0.62) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL16151090 | 0.83 | HDAC6 (0.68) | HDAC6CETPHSPD1PTPN2PTPN1 | |
| SCHEMBL26269798 | 0.82 | NPC1 (0.48) | HDAC6SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1733840 | 0.82 | HDAC6 (0.60) | HDAC6SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2137065 | 0.81 | SMN1; SMN2 (0.54) | HDAC6SMN1; SMN2NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126270-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) | 2010-11-04 | — | — | WO | disclosed |