SCHEMBL25875857

SCHEMBL25875857

N#Cc1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cc(-c5nc6ccccc6o5)cc(-c5nc6ccccc6o5)c4)n3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.49
RAB9A P51151 4/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
HDAC6 Q9UBN7 1/20 0.47
ABCG2 Q9UNQ0 5/20 0.44
ABCB1 P08183 2/20 0.44
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 3/20 0.44
SMN1; SMN2 Q16637 5/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 4/20 0.43
TP53 P04637 2/20 0.43
HSPD1 P10809 1/20 0.42
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN5 P54829 1/20 0.42
HSPE1 P61604 1/20 0.42
PSMB8 P28062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26269798 0.99 NPC1 (0.48) NPC1RAB9AMEN1KMT2AATM
SCHEMBL25875041 0.87 TP53 (0.43) NPC1RAB9AMEN1KMT2AATM
SCHEMBL28698089 0.86 GPR119 (0.49) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13067548 0.85 NPC1 (0.62) NPC1RAB9AMEN1KMT2AATM
SCHEMBL25875202 0.84 PTGS2 (0.47) NPC1RAB9AMEN1KMT2AATM
SCHEMBL23079688 0.84 NPC1 (0.68) NPC1RAB9AMEN1KMT2AATM
SCHEMBL9680833 0.84 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13067482 0.83 HDAC6 (0.56) NPC1RAB9AHDAC6SMN1; SMN2KDM4E
SCHEMBL24184418 0.83 NPC1 (0.58) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27049315 0.83 NPC1 (0.58) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140649-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-27 WO disclosed