Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368066 | 0.85 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL14370514 | 0.84 | ACACB (0.58) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL12323563 | 0.84 | ACACB (0.58) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL1412240 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL3948856 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL1412238 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL29519545 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL13880696 | 0.84 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL5059304 | 0.84 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2ADRB1 | |
| SCHEMBL5059309 | 0.84 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996544-B1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | ZENTIVA KS (CZ) | 2010-11-10 | — | — | EP | disclosed |