Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072835 | 0.90 | MAPT (0.47) | GAAMAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL1083426 | 0.89 | MAPT (0.47) | GAAMAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL12706981 | 0.88 | TP53 (0.47) | GAAMAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL13762949 | 0.83 | ACKR3 (0.50) | MAPTTP53POLBSMN1; SMN2RXFP1 | |
| SCHEMBL1549596 | 0.82 | ACKR3 (0.62) | MAPTTP53POLBSMN1; SMN2RXFP1 | |
| SCHEMBL1074684 | 0.80 | ACKR3 (0.47) | MAPTTP53POLBSMN1; SMN2RXFP1 | |
| SCHEMBL3399997 | 0.80 | ACKR3 (0.47) | GAAMAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL13069583 | 0.78 | ACKR3 (0.44) | GAAMAPTTP53POLBRXFP1 | |
| SCHEMBL13762953 | 0.75 | THRB (0.46) | GAAMAPTTP53POLBRXFP1 | |
| SCHEMBL14455249 | 0.75 | POLB (0.64) | GAAMAPTTP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954274-B1 | SUBSTITUTED QUINOLONES AND METHODS OF USE | CHEMOCENTRYX INC (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2007059108-A2 | SUBSTITUTED QUINOLONES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-24 | — | — | WO | disclosed |