⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464820 | 1.00 | — | — | |
| SCHEMBL14819181 | 0.80 | MKNK1 (0.50) | — | |
| SCHEMBL2539433 | 0.78 | — | — | |
| Formic Acid Phenyl Ester SCHEMBL5917638 | 0.78 | TSHR (0.39) | — | |
| SCHEMBL601438 | 0.78 | — | — | |
| SCHEMBL7771216 | 0.78 | — | — | |
| SCHEMBL13665334 | 0.78 | — | — | |
| SCHEMBL7905693 | 0.75 | LMNA (0.47) | — | |
| SCHEMBL4189876 | 0.75 | LMNA (0.47) | — | |
| SCHEMBL4189879 | 0.75 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102387800-B | Rosuvastatin and atorvastatin derivatives | REDX PHARMA LTD | 2013-11-27 | — | — | CN | claimed |
| CN-102839379-A | On-line treatment method of acidic etching solution | CHONGQING KOOPPER CHEMICAL INDUSTRY CO LTD | 2012-12-26 | — | — | CN | claimed |
| CN-102387799-A | Use of atorvastatin lactol as a medicament | BRADFORD PHARMA LTD | 2012-03-21 | — | — | CN | claimed |
| CN-102387800-A | Rosuvastatin and atorvastatin derivatives | BRADFORD PHARMA LTD | 2012-03-21 | — | — | CN | claimed |
| CN-102387837-A | Use of rosuvastatin lactols as medicaments | BRADFORD PHARMA LTD | 2012-03-21 | — | — | CN | claimed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | claimed |
| CN-1021819-C | PROCESS FOR DIUREA DERIVATIVES USEFUL AS MEDICAMENTS | YAMANOUCHI PHARMA CO LTD (JP) | 1993-08-18 | — | — | CN | claimed |
| CN-111201228-B | 6-amino-7, 9-dihydro-8H-purin-8-one derivatives as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20210309619-A1 | ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-11109593-B2 | Isoxazolin-5-one derivative and herbicide containing same as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-09-07 | — | — | US | disclosed |
| EP-3828176-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2021-06-02 | — | — | EP | disclosed |
| US-20200267985-A1 | ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| WO-2020022350-A1 | ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | 北興化学工業株式会社 | 2020-01-30 | — | — | WO | disclosed |
| US-4631339-A | 1,3,5-triazepinones | ELI LILLY AND COMPANY (US) | 1986-12-23 | — | — | US | disclosed |
| US-4594313-A | Containing hetero rings | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4514564-A | 7β-(2'-(1\",3\",5\"-Triazepin-4\"-one)-2'-(oxime ether)-acetamido)-3-substituted cephalosporins | ELI LILLY AND COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| US-4436912-A | 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido cephalosporin antibiotics and intermediates therefor | ELI LILLY AND COMPANY (US) | 1984-03-13 | — | — | US | disclosed |
| US-4430499-A | 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido]cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |