Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 17/20 | 0.44 |
| ▸ | GSK3B | P49841 | 7/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069617 | 0.85 | DYRK1A (0.43) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL2088796 | 0.85 | DYRK1A (0.59) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL2086068 | 0.85 | DYRK1A (0.59) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL2086694 | 0.85 | DYRK1A (0.59) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL2087846 | 0.83 | DYRK1A (0.46) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL13069122 | 0.81 | DYRK1A (0.44) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL14391202 | 0.81 | DYRK1A (0.42) | USP30DYRK1AGSK3BWNT1 | |
| SCHEMBL15199687 | 0.80 | DYRK1A (0.44) | USP30DYRK1AGSK3BPAK1WNT1 | |
| SCHEMBL13069625 | 0.80 | DYRK1A (0.52) | DYRK1AGSK3BWNT1 | |
| SCHEMBL1966893 | 0.79 | CHRNA7 (0.61) | USP30DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742944-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2010-11-10 | — | — | EP | disclosed |