Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.80 |
| ▸ | PGR | P06401 | 4/20 | 0.77 |
| ▸ | AR | P10275 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | HRH1 | P35367 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | FNTA | P49354 | 1/20 | 0.64 |
| ▸ | FNTB | P49356 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.60 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394713 | 1.00 | NR3C1 (0.80) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL21231580 | 1.00 | NR3C1 (0.80) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL3394719 | 1.00 | NR3C1 (0.80) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL7616035 | 0.92 | NR3C1 (0.80) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL3406859 | 0.92 | NR3C1 (0.80) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL11814061 | 0.90 | NR3C1 (0.77) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL11814068 | 0.90 | NR3C1 (0.77) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL8735123 | 0.90 | NR3C1 (0.87) | NR3C1PGRARHSD17B10HIF1A | |
| SCHEMBL8735124 | 0.90 | NR3C1 (0.87) | NR3C1PGRARHSD17B10HIF1A | |
| Fludrocortisone SCHEMBL21297043 | 0.89 | NR3C1 (0.96) | NR3C1PGRARHSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122096-A1 | PROCESS FOR OBTAINING FLUOROMETHOLONE AND INTERMEDIATES THEREFOR | CRYSTAL PHARMA, S.L.U. (ES) | 2010-10-28 | — | — | WO | disclosed |