Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.87 |
| ▸ | PGR | P06401 | 3/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.80 |
| ▸ | HRH1 | P35367 | 1/20 | 0.80 |
| ▸ | AR | P10275 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | FNTA | P49354 | 1/20 | 0.69 |
| ▸ | FNTB | P49356 | 1/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735123 | 1.00 | NR3C1 (0.87) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL10598529 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL14373312 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL5188889 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL4323075 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL23975175 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL13026141 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL4545 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| Fludrocortisone SCHEMBL19327146 | 0.93 | NR3C1 (1.00) | NR3C1PGRHIF1AHRH1AR | |
| SCHEMBL11335111 | 0.92 | NR3C1 (0.84) | NR3C1PGRHIF1AHRH1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648229-B1 | HYALURONIC ACID AND DERIVATIVES THEREOF IN INTERPENETRATING POLYMER NETWORKS (IPN) | MURST ITALIAN (IT) | 1998-05-06 | — | — | EP | disclosed |
| US-5644049-A | Biomaterial comprising hyaluronic acid and derivatives thereof in interpenetrating polymer networks (IPN) | M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITITES AND SCIENTIFIC AND TECHNOLOGY RESEARCH (IT) | 1997-07-01 | — | — | US | disclosed |