Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12519066 | 0.84 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL15426045 | 0.84 | MEN1 (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL8191582 | 0.84 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL43231 | 0.84 | HPGD (0.36) | HPGDHTTSMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL18878682 | 0.83 | CASP2 (0.41) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL30360564 | 0.83 | SMN1; SMN2 (0.38) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL5499536 | 0.82 | PSMB8 (0.35) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL18250682 | 0.82 | SMN1; SMN2 (0.41) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL17750731 | 0.82 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL16724725 | 0.82 | HPGD (0.40) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907860-B1 | MASS LABELS | ELECTROPHORETICS LTD (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2007012849-A2 | MASS LABELS FOR BIOMOLECULES CONTAINING A 2,6-DIMETHYL-PIPERIDIN-l-YL METHYLENE OR A PYRIMIDIN-2-YL THIOMETHYLENE MASS MARKER MOIETY AND A SUCCINIMID-OXY-CARBONYL REACTIVE FUNCTIONAL GROUP | ELECTROPHORETICS LIMITED (GB) | 2007-02-01 | — | — | WO | disclosed |