Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531314 | 0.85 | ESR1 (0.52) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL9310053 | 0.79 | PTGS2 (0.52) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL4326009 | 0.78 | ESR1 (0.64) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL3314631 | 0.78 | ESR1 (0.61) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL8596721 | 0.78 | ESR1 (0.61) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL23641321 | 0.78 | ESR1 (0.50) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL9310275 | 0.78 | ESR1 (0.50) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL9310269 | 0.75 | ESR1 (0.56) | ESR1PTGS2CYP19A1ESR2CES2 | |
| SCHEMBL1043478 | 0.74 | CES2 (0.52) | ESR1PTGS2CES2CES1CYP3A4 | |
| SCHEMBL28154521 | 0.73 | ESR1 (0.48) | ESR1PTGS2CYP19A1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1491610-B1 | Organic electroluminescent device | CANON KK (JP) | 2010-11-24 | — | — | EP | disclosed |