Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | PGR | P06401 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271558 | 1.00 | HIF1A (0.67) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL3397721 | 1.00 | HIF1A (0.67) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL11272815 | 0.85 | CYP3A4 (0.49) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL9624264 | 0.83 | CYP3A4 (0.47) | HIF1ACYP3A4NR3C1PGRLMNA | |
| SCHEMBL11271575 | 0.82 | HIF1A (0.79) | HIF1ACYP3A4NR3C1PGRLMNA | |
| Fluorometholone SCHEMBL23975162 | 0.80 | HIF1A (1.00) | HIF1ACYP3A4NR3C1PGRLMNA | |
| Fluorometholone SCHEMBL9415488 | 0.80 | HIF1A (1.00) | HIF1ACYP3A4NR3C1PGRLMNA | |
| Fluorometholone SCHEMBL5187729 | 0.80 | HIF1A (1.00) | HIF1ACYP3A4NR3C1PGRLMNA | |
| Fluorometholone SCHEMBL13026152 | 0.80 | HIF1A (1.00) | HIF1ACYP3A4NR3C1PGRLMNA | |
| Fluorometholone SCHEMBL13069734 | 0.80 | HIF1A (1.00) | HIF1ACYP3A4NR3C1PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246359-A1 | Process for obtaining fluorometholone and intermediates therefor | Crystal Pharma, S.L.U. (ES) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010122096-A1 | PROCESS FOR OBTAINING FLUOROMETHOLONE AND INTERMEDIATES THEREFOR | CRYSTAL PHARMA, S.L.U. (ES) | 2010-10-28 | — | — | WO | disclosed |