Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271558 | 0.83 | HIF1A (0.67) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL3397721 | 0.83 | HIF1A (0.67) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL13069736 | 0.83 | HIF1A (0.67) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL9624042 | 0.82 | KDM4E (0.67) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL9623243 | 0.81 | ALDH1A1 (0.48) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL9623240 | 0.81 | ALDH1A1 (0.48) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL9623066 | 0.80 | CYP3A4 (0.41) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL11272815 | 0.79 | CYP3A4 (0.49) | CYP3A4HIF1APGRNR3C1LMNA | |
| SCHEMBL9623688 | 0.72 | CYP3A4 (0.68) | CYP3A4HIF1APGRNR3C1NR1I2 | |
| SCHEMBL10627552 | 0.72 | NR3C1 (0.47) | CYP3A4HIF1APGRNR3C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |