Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.59 |
| ▸ | PREP | P48147 | 2/20 | 0.59 |
| ▸ | FAP | Q12884 | 2/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13057112 | 1.00 | DPP4 (0.59) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL13070107 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL14000163 | 0.82 | ALDH1A1 (0.44) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL13070184 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL13997998 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL1677554 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL2418371 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL20977038 | 0.79 | DPP4 (0.41) | DPP4POLB | |
| SCHEMBL1631843 | 0.78 | DPP4 (0.58) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL8304001 | 0.78 | DPP4 (0.58) | DPP4DPP8DPP9PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865666-B1 | HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2017-05-31 | — | — | EP | disclosed |
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| EP-2813500-A1 | Intermediates for the preparation of hepatitis C virus inhibitors | Bristol-Myers Squibb Company (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-2246347-A1 | DICYCLOAZAALKANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2010-11-03 | — | — | EP | disclosed |
| EP-2133077-A1 | DERIVATIVES OF AZABICYCLO OCTANE, THE METHOD OF MAKING THEM AND THE USES THEREOF AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2009-12-16 | — | — | EP | disclosed |