Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.58 |
| ▸ | PREP | P48147 | 2/20 | 0.58 |
| ▸ | FAP | Q12884 | 2/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631839 | 1.00 | DPP4 (0.58) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL16935720 | 0.94 | DPP4 (0.51) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1632383 | 0.88 | — | — | |
| SCHEMBL1631028 | 0.85 | DPP4 (0.42) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1860907 | 0.82 | DPP4 (0.40) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1632768 | 0.82 | POLB (0.44) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL27937090 | 0.80 | EPHX2 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL27967587 | 0.80 | ALDH1A1 (0.44) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL13070051 | 0.78 | DPP4 (0.59) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL13057112 | 0.78 | DPP4 (0.59) | DPP4DPP8PREPFAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | claimed |
| EP-0952842-A2 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-11-03 | — | — | EP | claimed |
| EP-0605638-B1 | METAL ALKOXIDES | UNIV FLORIDA STATE (US) | 1999-09-01 | — | — | EP | claimed |
| WO-1997038664-A2 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-23 | — | — | WO | claimed |