Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3394567 | 0.99 | SLC2A1 (0.40) | SLC2A1CYP4F2MCHR1TLR7KDM1A | |
| SCHEMBL3394837 | 0.81 | GRIN2B (0.40) | SLC2A1KCNH2 | |
| SCHEMBL3394476 | 0.81 | JAK3 (0.36) | SLC2A1HRH3DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL3394572 | 0.78 | DRD3 (0.33) | KCNH2DRD3DRD2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3397317 | 0.77 | HRH3 (0.41) | MCHR1HRH3KCNH2DRD3DRD2 | |
| SCHEMBL13283595 | 0.74 | CYP4F2 (0.37) | CYP4F2MCHR1KDM1AHRH3ATM | |
| SCHEMBL4490726 | 0.72 | SLC2A1 (0.61) | SLC2A1HDAC6 | |
| SCHEMBL3397585 | 0.72 | SLC2A1 (0.43) | SLC2A1 | |
| SCHEMBL4487955 | 0.71 | SLC2A1 (0.66) | SLC2A1HDAC6 | |
| SCHEMBL3397533 | 0.71 | SLC2A1 (0.42) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |