Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | BRD2 | P25440 | 2/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397585 | 0.89 | SLC2A1 (0.43) | SLC2A1DGAT1BRD4BRD2BRD3 | |
| SCHEMBL13754686 | 0.80 | SLC2A1 (0.56) | SLC2A1MAT2ALMNABRD4CREBBP | |
| SCHEMBL3396956 | 0.80 | SLC2A1 (0.39) | SLC2A1KDM4EALDH1A1MAOBMAT2A | |
| SCHEMBL4469233 | 0.78 | SLC2A1 (0.52) | SLC2A1MEN1KMT2ABRD4CREBBP | |
| SCHEMBL4484452 | 0.77 | SLC2A1 (0.53) | SLC2A1 | |
| SCHEMBL4476932 | 0.77 | GPR84 (0.48) | SLC2A1KDM4EMAT2ASMN1; SMN2MEN1 | |
| SCHEMBL4490726 | 0.76 | SLC2A1 (0.61) | SLC2A1MAOBDGAT1 | |
| SCHEMBL4487955 | 0.75 | SLC2A1 (0.66) | SLC2A1DGAT1 | |
| SCHEMBL4493447 | 0.74 | SLC2A1 (0.52) | SLC2A1MAOBDGAT1 | |
| SCHEMBL4476493 | 0.74 | SLC2A1 (0.52) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010081904-A1 | 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS | GLAXO GROUP LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |