Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299744 | 0.98 | SHBG (0.50) | SHBGEPHX1EPHX2 | |
| SCHEMBL23902245 | 0.95 | SHBG (0.41) | SHBGEPHX1TDP1 | |
| SCHEMBL13464009 | 0.81 | SHBG (0.43) | SHBGEPHX1EPHX2 | |
| SCHEMBL13996012 | 0.81 | SHBG (0.36) | SHBGEPHX1TDP1HTT | |
| SCHEMBL170904 | 0.80 | SHBG (0.50) | SHBGEPHX1KDM4E | |
| SCHEMBL1870619 | 0.80 | SHBG (0.50) | SHBGEPHX1KDM4E | |
| SCHEMBL13995986 | 0.79 | SHBG (0.39) | SHBGEPHX1HTT | |
| SCHEMBL13995983 | 0.79 | SHBG (0.39) | SHBGEPHX1HTT | |
| SCHEMBL27394167 | 0.79 | SHBG (0.34) | SHBGEPHX1TDP1 | |
| SCHEMBL1864078 | 0.78 | SHBG (0.54) | SHBGEPHX1KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |