Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870619 | 1.00 | SHBG (0.50) | SHBGEPHX1KDM4ETP53GMNN | |
| SCHEMBL24351545 | 0.97 | — | — | |
| SCHEMBL1864078 | 0.97 | SHBG (0.54) | SHBGEPHX1KDM4ETP53GMNN | |
| SCHEMBL26404681 | 0.97 | SHBG (0.54) | SHBGEPHX1KDM4ETP53GMNN | |
| SCHEMBL27663102 | 0.92 | — | — | |
| SCHEMBL11915409 | 0.92 | — | — | |
| SCHEMBL24201428 | 0.83 | SHBG (0.34) | SHBG | |
| SCHEMBL21942855 | 0.81 | SHBG (0.43) | SHBGEPHX1 | |
| SCHEMBL13070487 | 0.80 | SHBG (0.46) | SHBGEPHX1KDM4E | |
| SCHEMBL25764901 | 0.80 | SHBG (0.41) | SHBGEPHX1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |