Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706164 | 0.87 | NOX1 (0.46) | NOX1L3MBTL1MEN1KMT2AADRA2A | |
| SCHEMBL23775819 | 0.83 | NOX1 (0.47) | NOX1L3MBTL1MEN1KMT2AADRA2A | |
| SCHEMBL11327462 | 0.82 | NOX1 (0.38) | NOX1L3MBTL1MEN1KMT2AADRA2A | |
| SCHEMBL2756479 | 0.81 | NOX1 (0.42) | NOX1L3MBTL1MEN1KMT2AADRA2A | |
| SCHEMBL19071936 | 0.80 | NOX1 (0.47) | CYP2D6NOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL629086 | 0.79 | MAOA (0.63) | CYP2D6NOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL2756738 | 0.78 | NOX1 (0.42) | NOX1L3MBTL1MEN1KMT2AADRA2A | |
| SCHEMBL13888145 | 0.76 | MAOA (0.63) | CYP2D6NOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL1102432 | 0.76 | MAOA (0.63) | CYP2D6NOX1L3MBTL1MEN1KMT2A | |
| SCHEMBL2739325 | 0.75 | SNCA (0.59) | CYP2D6NOX1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |