Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888145 | 0.90 | MAOA (0.63) | MAOANOX1L3MBTL1LMNAMAPT | |
| SCHEMBL2659087 | 0.83 | MAOA (0.58) | MAOANOX1L3MBTL1LMNAMAPT | |
| SCHEMBL11258846 | 0.81 | MAOA (0.56) | MAOANOX1L3MBTL1LMNAMAPT | |
| SCHEMBL19071936 | 0.80 | NOX1 (0.47) | MAOANOX1L3MBTL1LMNAMAPT | |
| Metiazinic Acid SCHEMBL150554 | 0.80 | LMNA (0.59) | MAOANOX1L3MBTL1LMNAMAPT | |
| Metiazinic Acid SCHEMBL30190433 | 0.80 | LMNA (0.59) | MAOANOX1L3MBTL1LMNAMAPT | |
| Metiazinic Acid SCHEMBL30697757 | 0.80 | LMNA (0.59) | MAOANOX1L3MBTL1LMNAMAPT | |
| Metiazinic Acid SCHEMBL10820947 | 0.80 | LMNA (0.59) | MAOANOX1L3MBTL1LMNAMAPT | |
| SCHEMBL2669592 | 0.80 | MAOA (0.54) | MAOANOX1L3MBTL1LMNAMAPT | |
| SCHEMBL231247 | 0.80 | MAOA (1.00) | MAOANOX1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883987-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M Innovative Properties Company (US) | 2008-02-06 | — | — | EP | claimed |
| WO-2006124738-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-11-23 | — | — | WO | claimed |
| US-20060263697-A1 | Substituted phenothiazine redox shuttles for rechargeable lithium-ion cell | 3M INNOVATIVE PROPERTIES COMPANY | 2006-11-23 | — | — | US | claimed |
| US-8304409-B2 | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use | NICOX S.A. (FR) | 2012-11-06 | — | — | US | disclosed |
| EP-1883987-B1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M INNOVATIVE PROPERTIES CO (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20100093671-A1 | NITROSATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NICOX SA (FR) | 2010-04-15 | — | — | US | disclosed |
| US-7615312-B2 | Electrolytic cells; phenothiazine compound has oxidation potential above positive electrode recharged potential and serves as cyclable redox chemical shuttle providing cell overcharge protection | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-11-10 | — | — | US | disclosed |
| EP-1883987-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M Innovative Properties Company (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006124738-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060263697-A1 | Substituted phenothiazine redox shuttles for rechargeable lithium-ion cell | 3M INNOVATIVE PROPERTIES COMPANY | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093671-A1 | NITROSATED NONSTEROIDAL ANTIINFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NOS2, NOS1, NOS3 | MAOA 990/4885NOX1 37/4885L3MBTL1 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.