Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101483 | 0.77 | TSHR (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10187322 | 0.77 | CRHR1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10338079 | 0.77 | CYP2D6 (0.50) | CYP2D6CYP3A4CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL2757142 | 0.75 | PDGFRB (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL469910 | 0.75 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13154833 | 0.72 | ACACB (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7320740 | 0.71 | ACACB (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2358097 | 0.70 | SOAT1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2357938 | 0.70 | NR5A1 (0.49) | CYP2D6CYP3A4MEN1ALDH1A1LMNA | |
| SCHEMBL7151514 | 0.70 | SOAT1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |