Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244218 | 0.89 | KMT2A (0.33) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13071535 | 0.88 | ALDH1A1 (0.36) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13244215 | 0.88 | ALDH1A1 (0.33) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13070875 | 0.87 | ACACB (0.37) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13266737 | 0.87 | ALDH1A1 (0.35) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13071297 | 0.86 | LMNA (0.35) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13071277 | 0.81 | — | — | |
| SCHEMBL13071070 | 0.78 | ACACB (0.38) | — | |
| SCHEMBL15489561 | 0.77 | ALDH1A1 (0.35) | KMT2AALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13288547 | 0.76 | KMT2A (0.37) | KMT2APDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253207-A1 | Substituted phenyl acetic acid esters | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2216316-A1 | Phenyl acetic acid derivatives | Bayer CropScience Aktiengesellschaft (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2216317-A1 | Phenyl acetic acid halogenides | Bayer CropScience AG (DE) | 2010-08-11 | — | — | EP | disclosed |
| US-20100174084-A1 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
| US-20100174084-A1 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-07-08 | — | — | US | disclosed |
| US-7718186-B2 | 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-7718186-B2 | 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220973-A1 | 2-Alkoxy-6-Alkyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | DDT, PAOX, PTPRG | KMT2A 1494/4885ALDH1A1 1170/4885SMN1; SMN2 4498/4885 |
| US-20100174084-A1 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives | DDT, PAOX, PTPRG | KMT2A 1494/4885ALDH1A1 1170/4885SMN1; SMN2 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.