Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666295 | 0.88 | COXFA4 (0.58) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL14665991 | 0.88 | COXFA4 (0.58) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL12315471 | 0.88 | COXFA4 (0.59) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL14098879 | 0.85 | COXFA4 (0.64) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL3456476 | 0.85 | COXFA4 (0.77) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL3456379 | 0.85 | COXFA4 (0.64) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL12315592 | 0.83 | HSP90AA1 (0.55) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL3456434 | 0.80 | COXFA4 (0.62) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL13071315 | 0.80 | COXFA4 (0.57) | COXFA4HSP90AA1PDE10AOPRM1CTSB | |
| SCHEMBL14670211 | 0.77 | HSP90AA1 (0.49) | COXFA4HSP90AA1PDE10AOPRM1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253333-A2 | Contrast Agents for Myocardial Perfusion Imaging | Lantheus Medical Imaging, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |