Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315592 | 0.85 | HSP90AA1 (0.55) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL12315471 | 0.79 | COXFA4 (0.59) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL13071291 | 0.77 | COXFA4 (0.57) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL14098879 | 0.77 | COXFA4 (0.64) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL3456379 | 0.77 | COXFA4 (0.64) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL3456476 | 0.77 | COXFA4 (0.77) | HSP90AA1COXFA4PDE10AOPRM1LMNA | |
| SCHEMBL3456434 | 0.77 | COXFA4 (0.62) | HSP90AA1COXFA4PDE10AOPRM1LMNA | |
| SCHEMBL13071315 | 0.75 | COXFA4 (0.57) | HSP90AA1COXFA4PDE10AOPRM1LMNA | |
| SCHEMBL14665991 | 0.72 | COXFA4 (0.58) | HSP90AA1COXFA4PDE10AOPRM1NPC1 | |
| SCHEMBL14666295 | 0.72 | COXFA4 (0.58) | HSP90AA1COXFA4PDE10AOPRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130028837-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | HSP90AA1 1970/4885COXFA4 2119/4885PDE10A 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.