Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10161372 | 0.88 | BRD4 (0.40) | KMT2AALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL10196588 | 0.83 | FAAH (0.45) | FAAHKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL10197010 | 0.80 | PTPN1 (0.40) | FAAHHPGDCYP1A2CYP2C19 | |
| SCHEMBL13072478 | 0.80 | CNR2 (0.38) | CNR2KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL10196582 | 0.80 | THRA (0.40) | CNR2FAAHKMT2ACYP1A2CYP2C19 | |
| SCHEMBL10196117 | 0.79 | MEN1 (0.43) | CNR2KMT2AMEN1 | |
| SCHEMBL10107728 | 0.73 | FAAH (0.40) | CNR2FAAHKMT2AALDH1A1HPGD | |
| SCHEMBL10107723 | 0.73 | FAAH (0.40) | CNR2FAAHKMT2AALDH1A1CYP1A2 | |
| SCHEMBL10107750 | 0.73 | FAAH (0.40) | CNR2FAAHCYP1A2CYP2C19 | |
| SCHEMBL17849870 | 0.73 | FAAH (0.39) | CNR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132670-A2 | PENTACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2010-11-18 | — | — | WO | disclosed |