SCHEMBL13073079

SCHEMBL13073079

COC(=O)N(NC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Cl)cn1-c1ncccc1Cl)C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 11/20 0.35
RBP4 P02753 1/20 0.34
F10 P00742 1/20 0.33
CHRNA7 P36544 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
GRM4 Q14833 1/20 0.31
DRD4 P21917 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12527962 0.96 MALT1 (0.34) MALT1RBP4F10CHRNA7TRPV1
SCHEMBL12559362 0.93 MALT1 (0.34) MALT1RBP4F10CHRNA7GRM4
SCHEMBL13072534 0.93 MALT1 (0.34) MALT1RBP4F10
SCHEMBL12527959 0.89 MALT1 (0.33) MALT1RBP4F10
SCHEMBL12527987 0.89 MALT1 (0.33) MALT1RBP4F10CHRNA7GRM4
SCHEMBL12528654 0.86 MALT1 (0.39) MALT1RBP4F10TRPV1GRM4
SCHEMBL13318607 0.86 MALT1 (0.35) MALT1RBP4F10CHRNA7TRPV1
SCHEMBL12559626 0.86 ALDH1A1 (0.39) MALT1RBP4F10CHRNA7TRPV1
SCHEMBL950805 0.86 MALT1 (0.39) MALT1F10TRPV1GRM4DRD4
SCHEMBL14495219 0.85 MALT1 (0.38) MALT1RBP4F10TRPV1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 US disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 MALT1 4850/4885RBP4 1463/4885F10 976/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB MALT1 4804/4885RBP4 1490/4885F10 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.