SCHEMBL13074604

SCHEMBL13074604

CSCCC(=O)N(C)c1sc(-c2cncc(F)c2)nc1N

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 2/20 0.33
PIK3CG P48736 1/20 0.32
DYRK1A Q13627 3/20 0.32
PIM1 P11309 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
CDC7 O00311 1/20 0.31
DBF4 Q9UBU7 1/20 0.31
TLR7 Q9NYK1 7/20 0.31
CHRM4 P08173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13048489 0.90 PIK3CG (0.34) PIK3CGDYRK1APIM1TRPM8PTGDR2
SCHEMBL13074683 0.88 PIK3CG (0.33) PIK3CGDYRK1ATRPM8PTGDR2
SCHEMBL13047453 0.88 PIK3CG (0.33) PIK3CGDYRK1ATRPM8PTGDR2CDC7
SCHEMBL13048666 0.88 PIK3CG (0.32) PIK3CGDYRK1ATRPM8PTGDR2
SCHEMBL13048092 0.88 PIK3CG (0.32) PIK3CGDYRK1ATRPM8PTGDR2
SCHEMBL14788428 0.86 PIK3CG (0.31) PIK3CGDYRK1ATRPM8PTGDR2
SCHEMBL290286 0.85 TRPM8 (0.32) PIK3CGDYRK1ATRPM8
SCHEMBL13047814 0.81 PIK3CG (0.33) PIK3CGDYRK1ATRPM8PTGDR2CDC7
SCHEMBL290654 0.81 ABL1 (0.35) PIK3CGPTGDR2CDC7DBF4
SCHEMBL18569529 0.80 TRPM8 (0.34) PIK3CGDYRK1APIM1TRPM8PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010129497-A1 PESTICIDAL COMPOSITIONS DOW AGROSCIENCES LLC (US) 2010-11-11 WO disclosed