Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | LOX | P28300 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKLR | P30613 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835692 | 1.00 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL14486413 | 1.00 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL18069681 | 0.93 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL17472319 | 0.93 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL19008825 | 0.93 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL14148915 | 0.93 | PKM (0.86) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL13665511 | 0.91 | PKM (0.83) | PKMGAARAPGEF4HSD11B1HTT | |
| SCHEMBL2900381 | 0.91 | PKM (0.83) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL15908246 | 0.91 | PKM (0.83) | PKMGAARAPGEF4HSD11B1HTT | |
| SCHEMBL825670 | 0.91 | PKM (0.83) | PKMGAARAPGEF4HSD11B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216820-B1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | BOEING CO (US) | 2020-09-23 | — | — | EP | disclosed |
| US-20180009949-A1 | DINADIC PHENYL AMINE REACTIVE ENDCAPS | THE BOEING COMPANY | 2018-01-11 | — | — | US | disclosed |
| US-20170260332-A1 | POLYARYLETHER KETONE IMIDE ADHESIVES | THE BOEING COMPANY | 2017-09-14 | — | — | US | disclosed |
| US-20170260432-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | THE BOEING COMPANY | 2017-09-14 | — | — | US | disclosed |
| US-7825211-B2 | Single-step-processable polyimides | THE BOEING COMPANY (US) | 2010-11-02 | — | — | US | disclosed |
| US-20080319159-A1 | SINGLE-STEP-PROCESSABLE POLYIMIDES | THE BOEING COMPANY | 2008-12-25 | — | — | US | disclosed |
| US-20080300374-A1 | DINADIC PHENYL AMINE REACTIVE ENDCAPS | THE BOEING COMPANY | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009949-A1 | DINADIC PHENYL AMINE REACTIVE ENDCAPS | PARN, AADAC, PARG | PKM 2865/4885GAA 3531/4885RAPGEF4 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.